As of December 31st, 2019, the TLS 1.0 protocol will no longer be supported by Agilent, including older browsers (e.g. IE 10, Safari 6, Firefox 26 and older) and users will not have access to the iLab sites. Please click here for more information.

UTSW Structural Biology Laboratory

Overview of Services

The Structural Biology Laboratory (SBL) provides access and assistance with the techniques of X-ray crystallography and single particle cryo-electron microscopy reconstruction, and assistance with structure determination, refinement and interpretation. For X-ray this includes assistance with crystal screening and optimization, in-house X-ray diffraction screening and data collection, synchrotron data collection at the Advanced Photon Source (APS) for single crystals and Small Angle X-ray Scattering (SAXS) measurements. For single particle cryo-EM, this includes assistance with protein sample preparation, grid preparation for negative staining and cryo-EM, grid optimization, collection, processing and analysis of data from in-house microscopes, structure determination and validation.

Core Staff

Diana Tomchick, Ph.D.




Zhe (James) Chen, Ph.D.



Yang Li, Ph.D.



Helen Aronovich

Research Technician




Location and hours of operation

Hours Location

Monday - Friday

9 AM - 5 PM

24/7 Availability for trained instrument usage    

ND Building, floors 8 & 10

6001 Forest Park Rd.

Dallas, TX 75390-8816

Links and Resources


Name Role Phone Email Location
Diana Tomchick, Ph.D.

Service List

Search available services: View: by category alphabetically
Consumables, EM (7)
Consumables, X-ray (12)
Data collection & structure determination, EM (10)
Data collection and structure determination, X-ray (7)
Instrument Use, X-ray (2)