UTSW Structural Biology Laboratory

Pack of 240 coverslips

Includes all consumables

Pack of 122 coverslips

Includes all consumables

Includes all consumables

Includes all consumables

Includes all consumables

Includes all consumables

Charge if user supplies their own robotic crystallization plate

Includes all consumables

From 2D to 3D refinement/postprocessing.

Including 2D class selection-> 3D initial model -> 3D classification/analysis -> 3D refinement -> postprocessing and analysis with FSC curves. 

Please note: The rates listed below are cumulative and are based on a straightforward SPA workflow with a homogeneous dataset. Additional charges at an hourly rate per user classification would be added for more difficult projects. Users would be notified beforehand under such circumstances. 

Final CTF refinement and particle polishing (requires Relion motion correction step).

Please note: The rates listed are cumulative and are based on a straightforward SPA workflow with a homogeneous dataset. Additional charges at an hourly rate per user classification would be added for more difficult projects. Users would be notified beforehand under such circumstances. 

This is for day one of training on Aquilos II without the instrument charges by CEMF. This includes the staff time (6hr) and Vitrobot usage and comsumables.

These are the per day charges for Aquilos II time, as determined by the CEMF (Cryo-EM Facility).

for clipping cryo-EM grid to form an Autogrid

This is the first step of analyzing the feasibility of crosslink during cryoEM sample optimization. SBL will test up to 4 different crosslink conditions using glutaraldehide, after which, the reactions would be quenched and ready for further analysis such as using mass photometry (additional charge applies from MBR). The price listed is per protein sample. 

Includes per hour charge for Vitrobot, plasma cleaner and autoGrid station usage.

Only available to internal users.

These are the per hour charges for microscope time, as determined by the CEMF (Cryo-EM Facility).

Only available to internal users.

These are the per hour charges for microscope time, as determined by the CEMF (Cryo-EM Facility).

c-clip and clip ring for cryo-FIB grids, as a pair

Sample shipping both to and from synchrotron via FedEx.

Prices are per sample.

Service not available for commercial customers.

Trained or self use of crystallization robot; users will be charged for per plate usage, see charges under "Consumables, X-ray".

Price includes a $66/hour instrument usage for internal users.

Instrument usage costs are higher for other users.

This is a flat fee; price does NOT include per hour instrument usage.

This is a flat fee; price does NOT include the per hour instrument usage.

Covers dewar preparation services only.

Covers dewar preparation services and FedEx charges.

for negative stain EM

for cryo-EM data collection

for cryo-EM data collection

for cryo-EM data collection

for cryo-EM data collection

for cryo-EM data collection

for cryo-EM data collection

For screening samples prior to screening by cryo-EM data and/or data collection.

For screening samples prior to screening by cryo-EM data and/or data collection.

for storage of frozen, clipped grids in liquid nitrogen

for storage of frozen, unclipped grids in liquid nitrogen.

Price includes per hour charges for instrument usage as determined by the CEMF (Cryo-EM Facility).

Price includes per hour charges for instrument usage as determined by the CEMF (Cryo-EM Facility).

Assisted data collection, processing and scaling of in-house single-crystal data, per dataset

From movies to 2D classification.

Including motion correction (if needed) -> CTF estimate -> particle picking/selection -> 2D classification/analysis. 

Please note: The rates listed below are cumulative and are based on a straightforward SPA workflow with a homogeneous dataset. Additional charges at an hourly rate of $60/hour would be added for more difficult projects. Users would be notified beforehand under such circumstances. 

Charge for liquid nitrogen for storage dewars. Amount charged is equivalent to one 240-liter tank.

This is a passthrough charge from MBR. The rate is per measurement. 

for carbon coated grid preparation

Prices are per hour basis.

Robotic crystal screening of frozen samples.

Prices are per hour basis.

Assisted usage only.

for in situ screening and data collection of 96-condition crystallization screen plates.

Prices are per hour basis.

Assisted usage only.

Room temperature only.

Could include generation of figures and tables, description of methods, manuscript text and deposition of coordinates in database (PDB and/or EMDB). The cost will depends on the complexity of the project/data involved. SBL staff assisted hourly rate of approximately $65.5/hr applies. Please contact SBL for details.

0.22 micron filter for proteins

Screen includes all consumables: tray, screen and sealing tapes.

Determined after trip is finished; costs to be shared by all users during specific data collection time.

Service not available to commercial customers.

Includes data collection, structure determination, refinement and delivery of all data required for publication.

Project Specific.

Assisted collection, processing and scaling of synchrotron single crystal X-ray data, per dataset.

Service not available to commercial customers.

Collection in one buffer @ 3 concentrations.

Service not available to commercial customers.

c-clip and clip ring for cryo-FIB grids, as a pair

for cryo-EM data collection

for cryo-EM data collection

for cryo-EM data collection

for clipping cryo-EM grid to form an Autogrid

for cryo-EM data collection

for cryo-EM data collection

for negative stain EM

for cryo-EM data collection

for storage of frozen, clipped grids in liquid nitrogen

for storage of frozen, unclipped grids in liquid nitrogen.

for carbon coated grid preparation

Charge for liquid nitrogen for storage dewars. Amount charged is equivalent to one 240-liter tank.

Screen includes all consumables: tray, screen and sealing tapes.

Charge if user supplies their own robotic crystallization plate

0.22 micron filter for proteins

Includes all consumables

Includes all consumables

Includes all consumables

Includes all consumables

Includes all consumables

Includes all consumables

Includes all consumables

Pack of 240 coverslips

Pack of 122 coverslips

This is for day one of training on Aquilos II without the instrument charges by CEMF. This includes the staff time (6hr) and Vitrobot usage and comsumables.

These are the per day charges for Aquilos II time, as determined by the CEMF (Cryo-EM Facility).

This is the first step of analyzing the feasibility of crosslink during cryoEM sample optimization. SBL will test up to 4 different crosslink conditions using glutaraldehide, after which, the reactions would be quenched and ready for further analysis such as using mass photometry (additional charge applies from MBR). The price listed is per protein sample. 

This is a passthrough charge from MBR. The rate is per measurement. 

Price includes per hour charges for instrument usage as determined by the CEMF (Cryo-EM Facility).

Only available to internal users.

These are the per hour charges for microscope time, as determined by the CEMF (Cryo-EM Facility).

This is a flat fee; price does NOT include per hour instrument usage.

Price includes per hour charges for instrument usage as determined by the CEMF (Cryo-EM Facility).

Only available to internal users.

These are the per hour charges for microscope time, as determined by the CEMF (Cryo-EM Facility).

This is a flat fee; price does NOT include the per hour instrument usage.

From movies to 2D classification.

Including motion correction (if needed) -> CTF estimate -> particle picking/selection -> 2D classification/analysis. 

Please note: The rates listed below are cumulative and are based on a straightforward SPA workflow with a homogeneous dataset. Additional charges at an hourly rate of $60/hour would be added for more difficult projects. Users would be notified beforehand under such circumstances. 

From 2D to 3D refinement/postprocessing.

Including 2D class selection-> 3D initial model -> 3D classification/analysis -> 3D refinement -> postprocessing and analysis with FSC curves. 

Please note: The rates listed below are cumulative and are based on a straightforward SPA workflow with a homogeneous dataset. Additional charges at an hourly rate per user classification would be added for more difficult projects. Users would be notified beforehand under such circumstances. 

Final CTF refinement and particle polishing (requires Relion motion correction step).

Please note: The rates listed are cumulative and are based on a straightforward SPA workflow with a homogeneous dataset. Additional charges at an hourly rate per user classification would be added for more difficult projects. Users would be notified beforehand under such circumstances. 

Could include generation of figures and tables, description of methods, manuscript text and deposition of coordinates in database (PDB and/or EMDB). The cost will depends on the complexity of the project/data involved. SBL staff assisted hourly rate of approximately $65.5/hr applies. Please contact SBL for details.

Includes per hour charge for Vitrobot, plasma cleaner and autoGrid station usage.

For screening samples prior to screening by cryo-EM data and/or data collection.

For screening samples prior to screening by cryo-EM data and/or data collection.

Price includes a $66/hour instrument usage for internal users.

Instrument usage costs are higher for other users.

Covers dewar preparation services and FedEx charges.

Covers dewar preparation services only.

Sample shipping both to and from synchrotron via FedEx.

Prices are per sample.

Service not available for commercial customers.

Assisted collection, processing and scaling of synchrotron single crystal X-ray data, per dataset.

Service not available to commercial customers.

Determined after trip is finished; costs to be shared by all users during specific data collection time.

Service not available to commercial customers.

Collection in one buffer @ 3 concentrations.

Service not available to commercial customers.

Robotic crystal screening of frozen samples.

Prices are per hour basis.

Assisted usage only.

for in situ screening and data collection of 96-condition crystallization screen plates.

Prices are per hour basis.

Assisted usage only.

Room temperature only.

Assisted data collection, processing and scaling of in-house single-crystal data, per dataset

Project Specific.

Includes data collection, structure determination, refinement and delivery of all data required for publication.

Trained or self use of crystallization robot; users will be charged for per plate usage, see charges under "Consumables, X-ray".

Prices are per hour basis.