UTSW Metabolic Phenotyping Core

NEWS

Effective Immediately (11-21-2019)
 
To use the scintillation counter please make reservations using the iLab portal (24 hours in advance).

*Scintillation counter ONLY available during business hours (M-F 9:00 am-5:30 pm. Not available during holidays).

*Please make sure you sign-in the log spreadsheet located next to the instrument.

Effective Monday December 2nd 2019

Back in service 

*VITROS analysis requests from Monday-Friday and rush orders.

In observance of the Winter Holiday Break, the Metabolic Phenotyping Core will be

Closed on Monday December 23rd, Tuesday December 24th and Wednesday December 25th 

Regular business will resume on Thursday December 26th.

Happy holidays!

Effective Friday 11-01-2019

Back in service 

*FPLC Serum/Plasma Lipoprotein Particles Fractionation.

*Urine Collection Cages for mice.

Effective Monday 08-19-2019 and until further notice.

Rush orders are not accepted.

Vitros and NEFA submissions only accepted on Wed, Thurs. and Fridays. 

          On Fridays, no sample drop-off after 3:00 pm and unstable metabolites are not accepted after 12:00 noon (NEFA, Total Ketones, 3HB, ALKP, ALT, LDH, UPRO.

The following services will not be provided.

* MIlliplex, Cytokines. As an option you can inquire the Genomics & Microarray Core Facility. https://microarray.swmed.edu/products/product/luminex-service-plate/

* SeaHorse Flux Analyzer

LOCATION L4-102

 Updated Core Hours of Operation: Mon-Fri (9:00 AM - 5:30 PM) 

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VITROS no sample drop-off on Fridays after 3:00 pm.

For analysis of unstable metabolites (NEFA, Total ketones, 3HB, ALKP, ALT, LDH UPRO) no sample drop-off on Fridays after 12:00 noon. Late sample submission fee will be applied (2x $price). Effective immediately (06-15-2018)

Rush order analysis additional fees will apply (2x$price) (01-01-2018)

NEW!! Please be aware of cancellation fees for CLAMP SERVICES.  Effective Immediately (11-01-2017)

Billing cycles occur at monthly intervals ususally in the first week of the following month. Please make sure your subledger will not be expired at the time of billing.

Thank you for your cooperation.

Overview of Services

The Metabolic Phenotyping Core (MMPC) provides state-of-the-art analytical and phenotypical measures to the scientific community both inside and outside UT Southwestern Medical Center.

Our goal is to expand the scope of techniques available to investigators, standardize key methodologies, and expedite the completion of research on diseases related to metabolic disorders (diabetes and obesity), cancer, aging neurological disorders, etc.

• Chemistry analysis using VITROS MicroSlide™ technology, ELISAs, and magnetic bead mapping multiplex technology
• Tissue extraction of cholesterol and triglyceride level
• Metabolic chambers for indirect gas calorimetry, activity, and food/water consumption
• Urine collection chambers
• Body composition analysis (MRI )
• Glucose-insulin clamp studies
• Seahorse XF-24(3) Extracellular Flux Analyzer for cellular metabolism studies
• Primary hepatocyte and β-cell isolation from mice or rats
• Sphingolipid profiling using LC-MS/MS technology
• Free Amiono Acids profiling using LC-MS/MS technology. For Metabolic preclinical and clinical studies (Not for diagnosis purposes).
• Exercise treadmills for mice and rats
• RNA Scope and Base Scope Hybridization

Leadership

Philipp Scherer, PhD.

Professor, PI

Philipp.Scherer@UTSouthwestern.edu

Joel Elmquist, D.V.M., PhD.

Professor, PI

joel.elmquist@UTSouthwestern.edu

Jay Horton, M.D.

Professor, PI

jay.horton@UTSouthwestern.edu

Ruth Gordillo, Ph.D.

Director

214-648-2566

Ruth.Gordillo@UTSouthwestern.edu

Syann Lee, Ph.D.

Co-Director

214-648-3782

Syann.Lee@UTSouthwestern.edu

Richard (Max) Wynn, Ph.D.

Support Faculty

214-645-4405

Richard.Wynn@UTSouthwestern.edu

Staff 

Shannon Hacker

Research Technician II

214-645-4405

Shannon.Hacker@utsouthwestern.edu

Allison Walker

Research Technician II

214-645-4405

Allison.Walker@utsouthwestern.edu

Location and hours of operation

Links and Resources

1. http://touchstonelabs.org/metabolic-phenotyping-core/
2. https://www.utsouthwestern.edu/research/core-facilities/
3. http://www.utsouthwestern.edu/education/medical-school/departments/internal-medicine/divisions/touchstone-diabetes/index.html

Contacts